Why are low levels of plasmalogens bad?

Why are low levels of plasmalogens bad?

Plasmalogens and Death

There is no question that plasmalogens are important for health. But what about having low levels of plasmalogens – just how bad can it be? Dr. Goodenowe has made a lot of graphs in his career and only one graph has actually scared him: the relationship between blood plasmalogen levels and death.

Probability of Dying in 5.3 years

Data from the Rush University Memory and Aging Project. Final dataset: 1262 participants, participants still living since last clinical visit = 896, participants deceased since last visit = 862. The average age at enrollment = 81. Low plasmalogens = 5th percentile +/- 95% CI. High plasmalogens = 95th percentile +/- 95% CI.

Data from the Rush University Memory and Aging Project showed that a 95-year-old with high plasmalogen levels had the same chance of dying in five years as a 65-year-old with low plasmalogen levels. A 95-year-old with high levels had an almost 70 percent chance of living to their 100th birthday whereas a person the same age with low plasmalogen levels had a less than 20 percent chance of living to their 100th birthday. These results were shocking.

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