and helps maintain normal inflammatory balance.
ProdromeGlia™ – Omega-9 Plasmalogen Precursors for Brain, Myelin & White Matter Health
Supports healthy myelin structure, promotes white matter integrity,
Supports the Brain's Natural Renewal and Repair Processes
ProdromeGlia™ (Oil)
ProdromeGlia™ (Oil)
Regular price
$99.00 USD
Sale price
$99.00 USD
Regular price
ProdromeGlia™ (Softgels)
ProdromeGlia™ (Softgels)
Regular price
From $99.00 USD
Sale price
From $99.00 USD
Regular price
How to decide:
Choose softgels if you value convenience and portability.
Choose oil if you want faster absorption and flexible dosing.
ProdromeGlia™ provides high-potency Omega-9 plasmalogen precursors that help support healthy brain function, membrane integrity, and overall cellular health.*
At Prodrome Science, our mission is to deliver premium, science-based nutritional supplements designed to support lifelong wellness. Every product is manufactured in the USA in facilities that follow Good Manufacturing Practice (GMP) standards for safety and purity.
Trusted by healthcare professionals worldwide, Prodrome Science—founded by Dr. Dayan Goodenowe—remains dedicated to advancing plasmalogen research and innovation.
These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
What is ProdromeGlia™?
ProdromeGLIA is a high-quality dietary supplement formulated with Omega-9 lipids to support healthy brain structure and function. Plasmalogens are specialized lipids naturally found in the brain that help maintain myelin and white matter integrity. By providing key precursors, ProdromeGLIA helps support optimal neurological health, cognitive function, and overall brain wellness.
Why Plasmalogens & Myelin Matter
Plasmalogens are a unique class of ether phospholipids found in high concentrations in brain cell membranes, particularly in gray matter and myelin. They support:
- Membrane fluidity & synaptic function — allowing efficient signal transmission in neural tissues [1].
- Myelin sheath health — crucial for rapid axonal conduction; plasmalogen depletion is linked to demyelination and neural dysfunction [2].
- Gray matter support — polyunsaturated fatty acids in plasmalogens are enriched in gray matter and help with neuronal signaling, cognition, and memory [1].
Key Benefits Of ProdromeGlia™
Anti-Inflammatory Action
Plasmalogens influence neuroinflammation by suppressing activation of microglia and lowering pro-inflammatory cytokines such as IL-1β and TNF-α [3].
Protection & Repair of Myelin
Supplementation helps maintain plasmalogen levels and may influence remyelination while protecting myelin sheaths from oxidative damage [2].
Improve White Matter and Cognition
Higher plasmalogen levels are associated with better executive function and memory; observational studies show structural support for white matter [4].
Antioxidant & Anti-Amyloid Effects
The vinyl ether bond in plasmalogens gives them antioxidant capacity; they may influence amyloid accumulation and oxidative stress in neuro models [3].
Mood, Sleep, Mental Clarity
In a controlled human trial, oral plasmalogens influenced concentration, reduced fatigue and irritability, and enhanced
sleep quality [5].
Suggested Use & Safety
- Suggested Use: Take daily with a healthy fat source (or as directed by your provider).
- Safety: Plasmalogens show favorable tolerability in human studies.
This product is for health optimization and not intended to diagnose or treat disease [2,5].
Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Healthcare Professional Testimonials
What sets ProdromeGlia apart is that it fills a critical gap in patient care: true biochemical support for the brain and nervous system. Many products promise broad benefits, but this one delivers in a way that patients can feel and sustain. It’s a tool I trust deeply, and one I recommend as part of a comprehensive approach to thriving health.
Over the years, I’ve seen countless products come and go, but ProdromeGlia has earned a lasting place in my practice. It offers powerful, reliable support for cognitive performance and overall well-being. For patients committed to not just maintaining health but optimizing it, this is a product I recommend
without hesitation.
Prodrome Glia has become one of my go-to tools for supporting nerve health. In my practice, I’ve seen measurable benefits not only in clients with obvious neurologic challenges but also in high-level athletes—improvements in balance, speed, and coordination that align with Dr. Goodenowe’s research on nerve membrane repair. When we layer Prodrome Glia with Prodrome Neuro, the effect is even stronger, helping restore and optimize the phospholipid and plasmalogen pathways that underpin healthy nerve signaling.
References
- Udagawa J, Hino K. Plasmalogen in the brain: Effects on cognitive functions and behaviors attributable to its properties. Brain Res Bull. 2022 Oct 1;188:197-202. doi: 10.1016/j.brainresbull.2022.08.008. Epub 2022 Aug 12. PMID: 35970332.
- Su XQ, Wang J, Sinclair AJ. Plasmalogens and their protective role in oxidative stress and inflammation in the brain. Molecules. 2023;28(17):6328. doi:10.3390/molecules28176328.
- Ifuku M, Katafuchi T, Mawatari S, Noda M, Miake F, Sugiyama M, Fujino T. Anti-inflammatory/antioxidative effects of plasmalogens in lipopolysaccharide-induced neuroinflammation. J Neuroinflammation. 2012;9:197. doi:10.1186/1742-2094-9-197.
- Fujino T, Yamada T, Asada T, et al. Ethanolamine plasmalogen levels in the brain and cognitive function: evidence from human and animal studies. Neurosci Lett. 2022;768:136382. doi:10.1016/j.neulet.2022.136382.
- Fujino T, Hossain S, Mawatari S, et al. Oral administration of plasmalogens improves mental concentration, sleep, and fatigue: a randomized controlled trial. Front Cell Dev Biol. 2022;10:894734. doi:10.3389/fcell.2022.894734.