Understanding Plasmalogens

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Discover the remarkable power of plasmalogens, a vital component in our battle against aging and cognitive decline.

What Are Plasmalogens?

Plasmalogens are a vital class of phospholipids crucial for building cell membranes in the body. Their unique chemical structure, featuring a vinyl ether linkage at the sn-1 position of the glycerol backbone, grants them special properties essential for various functions, especially in the nervous system. These molecules are predominantly present in the brain, heart, lungs, eyes, and kidneys, comprising a significant portion, around 20%, of brain tissue. Beyond their structural role, plasmalogens act as key antioxidants and anti-inflammatory agents, playing a pivotal role in maintaining overall health and promoting longevity. Moreover, they are critically involved in nerve function, highlighting their indispensable nature in supporting neural processes and overall well-being.

What Do Plasmalogens Do?

Plasmalogens play a multifaceted role in supporting various physiological functions essential for overall health. They serve as powerhouses for our nerves, driving movements, thoughts, and vital processes like heartbeat and breathing. Additionally, plasmalogens contribute significantly to membrane integrity, fluidity, and cell signaling, while also acting as potent antioxidants. Their unique ability to restore and optimize cellular functions requiring high levels of omega-9, such as in brain white matter, myelin, and heart membranes, is crucial for maintaining cellular health and functionality. Moreover, plasmalogens support functions reliant on DHA, such as in brain gray matter, neuron function, and neuromuscular synaptic activity, thereby aiding in preventing neurodegeneration. Furthermore, they facilitate reverse cholesterol transport, reduce amyloid formation, improve cognition, enhance mobility, and mitigate lipid peroxidation, collectively contributing to overall well-being and longevity.

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  • Plasmalogens and Aging

    Plasmalogen levels begin to decrease after age 50. Persons with dementia exhibit a more rapid decrease in plasmalogens – especially omega-3 plasmalogens. ProdromeNEURO™ is designed to elevate omega-3 plasmalogens.
  • Plasmalogens and the Brain

    Plasmalogens are a critical component of brain membranes. The synaptic release of neurotransmitters (the core requirement for all nerve function) is dependent upon sufficient plasmalogen levels. Low brain plasmalogen levels are strongly correlated with reduced cognition.
  • Plasmalogens, Age, and All-Cause Mortality

    Dr. Goodenowe studied all-cause mortality in 1,262 elderly persons of whom 557 had subsequently died and 705 were still living. The 5-year probability of dying (by any cause) was discovered to be heavily dependent upon the person’s baseline blood plasmalogen levels. 5-year mortality in 85-year-olds with high plasmalogens was 20%, but was 70% in 85-year-olds with low plasmalogens. A 95-year-old with high plasmalogens had the same probability of living to age 100 as a 65-year-old with low plasmalogens had of living to age 70.

Plasmalogens are critical to all cells in the body.

Brain

Plasmalogens solidify and amplify the signals between neurons to optimize physical and cognitive performance.

Heart

Plasmalogens strengthen the heart muscle by reinforcing the cellular structure and function and preventing premature oxidation.

Blood

People with high blood plasmalogens were 80% less likely to experience dementia and are proven to live longer.

Hair & Nails

Plasmalogens in nail beds and hair follicles allow richer & thicker hair and healthier & faster-growing nails.

Cell Walls

Plasmalogens are the building blocks of healthy cells, including building and strengthening the myelin sheath in neuronal cells.

Aging

Antioxidant free radical that acts as the body’s first line of defense against oxidation, disease and aging.

Lungs

Plasmalogens promote and stabilize nonlamellar hexagonal phase structure and have significant antioxidant effects.

Eyes

Plasmalogens are vitally important in the membranes of neuronal tissues that link the brain and the retina. The higher the plasmalogen levels, the lower the risk of glaucoma.

Conclusion:

Having low plasmalogens is not worth the risk!

With no viable dietary sources available to replenish plasmalogen deficiencies, Dr. Goodenowe pioneered the development of targeted plasmalogen precursors, a groundbreaking invention designed to restore plasmalogen levels across all body cells.

These precursors, rigorously tested and validated through extensive preclinical and clinical research, are now accessible as innovative dietary supplements – ProdromeNEURO™ and ProdromeGLIA™. Additionally, Dr. Goodenowe's ProdromeSCAN™ offers a specialized blood test to accurately measure your plasmalogen levels, complementing your health regimen with precise, science-backed insights.

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